Revolution Medicines Inc Overview
Industry: Biotechnology
Sector: Healthcare
Revolution Medicines, Inc., a clinical-stage precision oncology company, develops therapies to inhibit frontier targets in RAS-addicted cancers. The company is developing RMC-4630, an inhibitor of SHP2, which is in Phase 1/2 clinical trial for the treatment of solid tumors, such as gynecologic tumors. It also develops RMC-5845, a selective inhibitor of SOS1, a protein that converts RAS (OFF) to RAS (ON) in cells; and RMC-5552, a hyperactivated selective inhibitor of mTORC1 signaling in tumors. In addition, the company is developing RMC-6291, a tri-complex inhibitor of KRASG12C(ON) and KRASG12C(ON); and RMC-6236, a RAS-selective inhibitor of multiple RAS(ON) variants. Further, it develops RAS(ON) Inhibitors targeting KRASG13C(ON) and KRASG12D(ON). The company has a collaboration agreement with Sanofi for the research and development of SHP2 inhibitors, including RMC-4630. Revolution Medicines, Inc. was incorporated in 2014 and is headquartered in Redwood City, California. Revolution Medicines, Inc., a clinical-stage precision oncology company, develops therapies to inhibit frontier targets in RAS-addicted cancers. The company is developing RMC-4630, an inhibitor of SHP2, which is in Phase 1/2 clinical trial for the treatment of solid tumors, such as gynecologic tumor Read MoreMavefund brings filings, fundamentals, valuation, price history and news for Revolution Medicines Inc into one research view. The sections below show what strengthens or weakens the research case.
Score
Reported Results
What the company reported, with filing details kept small.
Quarterly result summary
Net loss was -$644.4M (from $247.8M). R&D expense was $394.9M.
What changed
- Net loss was -$644.4M (from $247.8M).
Guidance / outlook
the company expects to initiate in the fourth quarter of 2026. Colorectal Cancer (CRC) The company continues to evaluate multiple combination approaches in CRC, including RAS(ON) inhibitor doublets and combinations with standard of care and other investigational therapies.
Source: SEC EDGAR company-filed earnings materials. Dates are shown only for verification; review the source filing before relying on extracted report details.
Other recent earnings materials
Prediction-grade evidence
Recent News
Company-relevant articles from sources that pass the Mave Signal relevance and reliability checks.
Revolution Medicines earnings in focus as FDA approval looms By Investing.com
Headline from Investing.com Nigeria: Revolution Medicines earnings in focus as FDA approval looms By Investing.com.
Revolution Medicines earnings in focus as FDA approval looms
Headline from Investing.com: Revolution Medicines earnings in focus as FDA approval looms.
Earnings call transcript: Revolution Medicines lifts spending outlook in Q2 2026
Headline from Investing.com: Earnings call transcript: Revolution Medicines lifts spending outlook in Q2 2026.
Revolution Medicines falls on second quarter earnings miss By Investing.com
Headline from Investing.com India: Revolution Medicines falls on second quarter earnings miss By Investing.com.
Revolution Medicines falls on second quarter earnings miss By Investing.com
Headline from Investing.com Nigeria: Revolution Medicines falls on second quarter earnings miss By Investing.com.
Revolution Medicines falls on second quarter earnings miss
Headline from Investing.com: Revolution Medicines falls on second quarter earnings miss.
Earnings Per Share
Return on Equity
ROE
Company —
Sector Median —
ROE
Company —
Sector Median —
ROE
Company —
Sector Median —
ROE
Company —
Sector Median —
Metric chart temporarily unavailable.
Net Margin
Net Margin
Company —
Sector Median —
Net Margin
Company —
Sector Median —
Net Margin
Company —
Sector Median —
Net Margin
Company —
Sector Median —
Metric chart temporarily unavailable.
Leverage
Leverage
Company —
Sector Median —
Leverage
Company —
Sector Median —
Leverage
Company —
Sector Median —
Leverage
Company —
Sector Median —
Metric chart temporarily unavailable.
Financial Statements
Company-reported SEC EDGAR facts organized into the three core statements.
Source: SEC EDGAR companyfacts. Values are standardized company filings for research support, not personalized financial advice.