MacroGenics Inc Overview
Industry: Biotechnology
Sector: Healthcare
MacroGenics, Inc., a biopharmaceutical company, develops and commercializes antibody-based therapeutics to treat cancer in the United States. Its approved product is MARGENZA (margetuximab-cmkb), a human epidermal growth factor receptor 2 (HER2) receptor antagonist indicated, in combination with chemotherapy, for the treatment of adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens. The company's pipeline of immuno-oncology product candidates includes MGC018, an antibody drug conjugate (ADC), which targets solid tumors expressing B7-H3; Enoblituzumab, a monoclonal antibody that targets B7-H3; and MGD024, an investigational bispecific CD123 � CD3 DART molecule to minimize cytokine-release syndrome for patients with hematologic malignancies. In addition, it develops Lorigerlimab, a monoclonal antibody that targets the immune checkpoints PD-1 and cytotoxic T-lymphocyte-associated protein 4; Tebotelimab, an investigational tetravalent DART molecule for PD-1 and lymphocyte-activation gene 3;Retifanlimab, an monoclonal antibody used for cancer therapeutics; and IMGC936, an ADC that targets ADAM9, a cell surface protein over-expressed in various solid tumor types. Further, the company develops MGD014 and MGD020, a DART molecule to target the envelope protein of human immunodeficiency virus infected cells and CD3 on T cells; Teplizumab for the treatment of type 1 diabetes; and PRV-3279, a CD32B � CD79B DART molecule for the treatment of autoimmune indications. It has collaborations with Incyte Corporation; Zai Lab Limited; I-Mab Biopharma; and Janssen Biotech, Inc. The company was incorporated in 2000 and is headquartered in Rockville, Maryland. MacroGenics, Inc., a biopharmaceutical company, develops and commercializes antibody-based therapeutics to treat cancer in the United States. Its approved product is MARGENZA (margetuximab-cmkb), a human epidermal growth factor receptor 2 (HER2) receptor antagonist indicated, in combination with che Read MoreMavefund brings filings, fundamentals, valuation, price history and news for MacroGenics Inc into one research view. The sections below show what strengthens or weakens the research case.
Score
Reported Results
What the company reported, with filing details kept small.
Quarterly result summary
Revenue was $20.8M (+58% YoY). Net loss was -$36.8M (from $41M). R&D expense was $35M.
What changed
- Revenue +58% YoY to $20.8M.
- Net loss was -$36.8M (from $41M).
Guidance / outlook
The Company anticipates reporting initial MGC026 clinical data in mid-2026. • MGC028 is a first-in-class ADC that targets ADAM9, which is overexpressed in multiple solid tumors.
Source: SEC EDGAR company-filed earnings materials. Dates are shown only for verification; review the source filing before relying on extracted report details.
Other recent earnings materials
Prediction-grade evidence
Recent News
Company-relevant articles from sources that pass the Mave Signal relevance and reliability checks.
MacroGenics slips on trial data for lead asset (MGNX:NASDAQ)
Headline from Seeking Alpha: MacroGenics slips on trial data for lead asset (MGNX:NASDAQ).
MGNX Jan 2027 6.000 call (MGNX270115C00006000) interactive stock chart
Headline from Yahoo Finance Singapore: MGNX Jan 2027 6.000 call (MGNX270115C00006000) interactive stock chart.
MacroGenics’ MGC026 meets Phase 1 trial milestone in SCCHN
Headline from Investing.com: MacroGenics’ MGC026 meets Phase 1 trial milestone in SCCHN.
MacroGenics’ MGC026 meets trial threshold in head and neck cancer
Headline from Investing.com: MacroGenics’ MGC026 meets trial threshold in head and neck cancer.
MacroGenics’ MGC026 meets Phase 1 trial milestone in SCCHN By Investing.com
Headline from Investing.com Canada: MacroGenics’ MGC026 meets Phase 1 trial milestone in SCCHN By Investing.com.
MacroGenics’ MGC026 meets trial threshold in head and neck cancer By Investing.com
Headline from Investing.com Canada: MacroGenics’ MGC026 meets trial threshold in head and neck cancer By Investing.com.
Earnings Per Share
Return on Equity
ROE
Company —
Sector Median —
ROE
Company —
Sector Median —
ROE
Company —
Sector Median —
ROE
Company —
Sector Median —
Metric chart temporarily unavailable.
Net Margin
Net Margin
Company —
Sector Median —
Net Margin
Company —
Sector Median —
Net Margin
Company —
Sector Median —
Net Margin
Company —
Sector Median —
Metric chart temporarily unavailable.
Leverage
Leverage
Company —
Sector Median —
Leverage
Company —
Sector Median —
Leverage
Company —
Sector Median —
Leverage
Company —
Sector Median —
Metric chart temporarily unavailable.
Financial Statements
Company-reported SEC EDGAR facts organized into the three core statements.
Source: SEC EDGAR companyfacts. Values are standardized company filings for research support, not personalized financial advice.