Aptevo Therapeutics Inc Overview
Industry: Biotechnology
Sector: Healthcare
Aptevo Therapeutics Inc., a clinical-stage biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company's lead clinical candidates are APVO436, a bispecific T-cell engaging antibody candidate that is in Phase 1b clinical trial for acute myelogenous leukemia and myelodysplastic syndromes; and. ALG.APV-527, an investigational bispecific ADAPTIR candidate that features a mechanism of action to target 4-1BB (CD137) and 5T4, a tumor antigen expressed in various types of cancers. Its preclinical candidates include APVO603, a dual agonist bispecific antibody to target 4-1BB and OX40; APVO711, a dual mechanism bispecific ADAPTIR candidate designed to provide synergistic stimulation of CD40 on antigen presenting cells; and APVO442, a bispecific candidate based on the ADAPTIR-FLEX platform technology to enhance biodistribution of drugs to PSMA positive tumors for treatment of prostate cancer. The company has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington. Aptevo Therapeutics Inc., a clinical-stage biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company's lead clinical candidates are APVO436, a bispecific T-cell engaging antibody candidate that is in Phase Read MoreMavefund brings filings, fundamentals, valuation, price history and news for Aptevo Therapeutics Inc into one research view. The sections below show what strengthens or weakens the research case.
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Reported Results
What the company reported, with filing details kept small.
Quarterly result summary
Net loss was -$26M. R&D expense was $14.5M.
Net loss
-$26M
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R&D expense
$14.5M
reported
What changed
- Review the SEC source filing for the full reported results and management commentary.
Guidance / outlook
No formal outlook was extracted from this filing excerpt. Open the SEC source to review full management commentary.
Earnings release
Open filing
Source: SEC EDGAR company-filed earnings materials. Dates are shown only for verification; review the source filing before relying on extracted report details.
Other recent earnings materials
SEC filing
8-K
May 13, 2026
SEC filing
10-Q
May 13, 2026
SEC filing
10-K
Mar 26, 2026
SEC filing
8-K
Mar 26, 2026
SEC filing
10-Q
Nov 06, 2025
Earnings release
Earnings release
Nov 06, 2025
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8-K
Nov 06, 2025
SEC filing
8-K
Aug 11, 2025
Earnings release
Earnings release
Aug 11, 2025
SEC filing
10-Q
Aug 11, 2025
Prediction-grade evidence
Recent News
Company-relevant articles from sources that pass the Mave Signal relevance and reliability checks.
APVO 8-K & SEC Filings
Headline from Yahoo Finance: APVO 8-K & SEC Filings.
APVO S-8 & SEC Filings
Headline from Yahoo Finance: APVO S-8 & SEC Filings.
Earnings Per Share
Score 2.00/5
Aptevo Therapeutics Inc earns a low score, as its Earnings Per Share (EPS) has not shown continuous growth over the last six years. Notable counterparts in the sector with high scores includes
Zoetis Inc
IQVIA Holdings Inc
Agilent Technologies Inc
In
Biotechnology industry
, Halozyme Therapeutics Inc
, Corcept Therapeutics Incorporated
, Exelixis Inc
are companies with high ratings.
Return on Equity
Score 0.25/5
Aptevo Therapeutics Inc exhibits a lower score in the Return on Equity (ROE) section, falling below the sector median value and indicating a comparatively weaker performance in this metric. The top companies in the same sector include
Zoetis Inc
IQVIA Holdings Inc
Agilent Technologies Inc
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Net Margin
Score 1.34/5
Aptevo Therapeutics Inc
olds a low score as its net margin consistently trails below the sector median value and doesn't exhibit continuous growth over the last six years; notable companies in the sector with commendable scores include
Zoetis Inc
IQVIA Holdings Inc
Agilent Technologies Inc
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Leverage
Score 1.39/5
Aptevo Therapeutics Inc
registers a lower score in the category as a result of its elevated leverage ratio over the past six years compared to the sector median value. Conversely, other companies in the same sector, including
Zoetis Inc
IQVIA Holdings Inc
Agilent Technologies Inc
have achieved high scores.
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Financial Statements
Company-reported SEC EDGAR facts organized into the three core statements.
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Source: SEC EDGAR companyfacts. Values are standardized company filings for research support, not personalized financial advice.
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